During 19 November 2016, a vaccine for both Ebola and Zika called EZDK-7 was developed by a joint medical research program by the US, Switzerland, Japan, Egypt and the UK.

After animal testing proved effective, the US began to extend testing to human subjects. The testing was mostly successful, with the exception of three test subjects, who developed rare and severe symptoms, believed to be a rare side effect of the vaccine. The vaccine was further examined, and results showed that one of the proteins created a chemical reaction under certain conditions, resulting in the complete collapse of the original vaccine structure and reconstruction of a new protein. Some biologists say that it no longer can be considered a protein as the amino acids have been "reformatted" to create a completely different building block, and what it does is exactly the opposite of what a protein does, making it very dangerous. The news soon reached all corners of the globe, including a rising power: ISIS.

The laboratory EZDK-7 was kept in was stormed by ISIS during the Invasion of Cairo circa March 2017. The vaccine was then modified to create an "antiprotein", with certain infectious viruses added to the mix.

After ISIS invaded Greece during  May 2017,they used planes to shower Eastern Europe with the antiprotein, nicknamed ISIS's weapon resulting in devastation in the biological composition of all life in the region. With the armies of powerful nations powerless, ISIS swiftly took the cities of Hungary, Romania and Bulgaria.

The developed countries of the world began research immediately to create an antidote for the antiprotein, and in August 2018, the antidote, PRQ-4 was deployed across ISIS antiprotein stockpiles via spies and bombed the production laboratories. With the biological weaponry gone, the world launched attacks on ISIS territories, and in February 2020, the presence of ISIS was wiped clean off the face of the Earth.